Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate
نویسندگان
چکیده
منابع مشابه
The Role of Glycoconjugates in Development of Floor Plate During Early Morphogenesis in Mouse Embryo
The floor plate is a small group of cells located at the ventral midline of neural tube. During early neurogenesis the floor plate plays critical role (s) in differentiation of ventral portion of neural tube.The purpose of this study was to determine the distribution of glycoconjugates in floor plate as well as underlying mesoderm (notochord) and their inductive activities in mouse embryos.Form...
متن کاملUnique Carbohydrate Appearance of the Floor Plate During Early Neurolation
During early neurogenesis, the floor plate plays an essential role(s) in the differentiation of the ventral portion of neural tube. In this study, we detected the specific distribution of unique glycoconjugate during the floor plate differentiation. Formalin fixed paraffin sections of BALB/c mice (10-14 embryonic days) were processed for histochemical studies using horseradish peroxidase-labell...
متن کاملA multiplex role for FOXA2 and SHH in floor plate specification and midbrain pattern formation
Many organs form by invaginating and rolling flat epithelial cell-sheets into tubes. Invagination of the ventral midline of the neural plate forms the median hinge point (MHP), an event that elevates the neural folds and is essential for neural tube closure (NTC). MHP formation involves dynamic spatiotemporal modulations of cell shape, but how these are achieved is not understood. We show that ...
متن کاملOpponent Activities of Shh and BMP Signaling during Floor Plate Induction In Vivo
We performed in vivo experiments in chick embryos that examined whether application of an exogenous source of Shh protein mimics the ability of the notochord to induce ectopic floor plate cells in the neural tube. Shh cannot act alone to induce a floor plate. However, coapplication of Shh and chordin, a BMP antagonist normally coexpressed with Shh in the notochord, results in a marked switch fr...
متن کاملunique carbohydrate appearance of the floor plate during early neurolation
during early neurogenesis, the floor plate plays an essential role(s) in the differentiation of the ventral portion of neural tube. in this study, we detected the specific distribution of unique glycoconjugate during the floor plate differentiation. formalin fixed paraffin sections of balb/c mice (10-14 embryonic days) were processed for histochemical studies using horseradish peroxidase-labell...
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ژورنال
عنوان ژورنال: EvoDevo
سال: 2018
ISSN: 2041-9139
DOI: 10.1186/s13227-017-0090-x